diff --git a/migrations_lockfile.txt b/migrations_lockfile.txt
index 73c2f3325101e0..a29668223d9ddd 100644
--- a/migrations_lockfile.txt
+++ b/migrations_lockfile.txt
@@ -29,7 +29,7 @@ releases: 0001_release_models
 
 replays: 0006_add_bulk_delete_job
 
-sentry: 0997_backfill_self_hosted_sentry_app_emails
+sentry: 0998_delete_never_active_users_without_emails_self_hosted
 
 social_auth: 0003_social_auth_json_field
 
diff --git a/src/sentry/migrations/0998_delete_never_active_users_without_emails_self_hosted.py b/src/sentry/migrations/0998_delete_never_active_users_without_emails_self_hosted.py
new file mode 100644
index 00000000000000..765c22724ff4da
--- /dev/null
+++ b/src/sentry/migrations/0998_delete_never_active_users_without_emails_self_hosted.py
@@ -0,0 +1,58 @@
+# Generated by Django 5.2.1 on 2025-10-21 23:09
+
+import logging
+
+from django.conf import settings
+from django.db import migrations, router
+from django.db.backends.base.schema import BaseDatabaseSchemaEditor
+from django.db.migrations.state import StateApps
+
+from sentry.new_migrations.migrations import CheckedMigration
+from sentry.silo.safety import unguarded_write
+
+logger = logging.getLogger(__name__)
+
+
+def delete_never_active_users_without_emails(
+    apps: StateApps, schema_editor: BaseDatabaseSchemaEditor
+) -> None:
+    if not settings.SENTRY_SELF_HOSTED:
+        # This operation for SaaS Sentry is handled using a script.
+        return
+
+    User = apps.get_model("sentry", "User")
+
+    target_users = User.objects.filter(last_active=None, email="")
+
+    for user in target_users:
+        logger.info("Deleting user %s", user.id)
+        with unguarded_write(using=router.db_for_write(User)):
+            user.delete()
+
+
+class Migration(CheckedMigration):
+    # This flag is used to mark that a migration shouldn't be automatically run in production.
+    # This should only be used for operations where it's safe to run the migration after your
+    # code has deployed. So this should not be used for most operations that alter the schema
+    # of a table.
+    # Here are some things that make sense to mark as post deployment:
+    # - Large data migrations. Typically we want these to be run manually so that they can be
+    #   monitored and not block the deploy for a long period of time while they run.
+    # - Adding indexes to large tables. Since this can take a long time, we'd generally prefer to
+    #   run this outside deployments so that we don't block them. Note that while adding an index
+    #   is a schema change, it's completely safe to run the operation after the code has deployed.
+    # Once deployed, run these manually via: https://develop.sentry.dev/database-migrations/#migration-deployment
+
+    is_post_deployment = True
+
+    dependencies = [
+        ("sentry", "0997_backfill_self_hosted_sentry_app_emails"),
+    ]
+
+    operations = [
+        migrations.RunPython(
+            delete_never_active_users_without_emails,
+            migrations.RunPython.noop,
+            hints={"tables": ["auth_user"]},
+        )
+    ]
diff --git a/tests/sentry/migrations/test_0998_delete_never_active_users_without_emails_self_hosted.py b/tests/sentry/migrations/test_0998_delete_never_active_users_without_emails_self_hosted.py
new file mode 100644
index 00000000000000..b72fa093ad61fd
--- /dev/null
+++ b/tests/sentry/migrations/test_0998_delete_never_active_users_without_emails_self_hosted.py
@@ -0,0 +1,23 @@
+from django.test import override_settings
+
+from sentry.testutils.cases import TestMigrations
+from sentry.testutils.silo import control_silo_test
+from sentry.users.models import User
+
+
+@control_silo_test
+@override_settings(SENTRY_SELF_HOSTED=True)
+class BackfillSelfHostedSentryAppEmailsTest(TestMigrations):
+    migrate_from = "0997_backfill_self_hosted_sentry_app_emails"
+    migrate_to = "0998_delete_never_active_users_without_emails_self_hosted"
+    connection = "control"
+
+    def setup_before_migration(self, apps):
+        self.target_user = self.create_user(username="froggy-chair", email="", last_active=None)
+        self.regular_user = self.create_user(username="regular@user", email="regular@user")
+
+        return super().setup_before_migration(apps)
+
+    def test(self) -> None:
+        assert User.objects.filter(id=self.target_user.id).first() is None
+        assert User.objects.filter(id=self.regular_user.id).first() == self.regular_user